LINC00511/HSA-MIR-573 AXIS-MEDIATED HIGH EXPRESSION OF GASDERMIN C ASSOCIATES WITH DISMAL PROGNOSIS AND TUMOR IMMUNE INFILTRATION OF BREAST CANCER

LINC00511/hsa-miR-573 axis-mediated high expression of Gasdermin C associates with dismal prognosis and tumor immune infiltration of breast cancer

Abstract Breast cancer (BC) is considered the second commonest human carcinoma and the most incident and mortal in the female population.Despite promising treatments for breast cancer, mortality rates of metastatic ornament ice cube molds disease remain high.Gasdermin C (GSDMC) is an affiliate of the gasdermin (GSDM) family, which is involved in th

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An evidence base to optimise methods for involving patient and public contributors in clinical trials: a mixed-methods study

Background: In comparison with other study designs, randomised trials are regarded as particularly likely to benefit from patient and public involvement (PPI).Using mixed-methods research we investigated PPI from the perspectives of researchers and PPI contributors.Methods: Randomised trials in receipt of funding from the Health Technology Assessme

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Drug involvement in fatal overdoses

copyright data from the Multiple Cause of Death (MCOD) zowie xl2546x files were analyzed to better understand the drug categories most responsible for the increase in fatal overdoses occurring between 1999 and 2014.Statistical adjustment methods were used to account for the understatement in reported drug involvement occurring because death certifi

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Revealing the stimulus-driven component of attention through modulations of auditory salience by timbre attributes

Abstract Attention allows the listener to select relevant information from their environment, and disregard what is irrelevant.However, irrelevant stimuli sometimes manage to capture it and stand out from a scene because of bottom-up processes driven by salient stimuli.This attentional capture effect was observed using an implicit approach based on

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Psychosocial assessment tools for use before transplantation are predictive of post-operative psychosocial and health behavior outcomes: a narrative review of the literature

IntroductionIn end-stage diseases, transplantation may be necessary.The limited number st1000nm0008 of donors led to the development of several pre-transplant psychosocial assessment tools.We summarized the predictive value of these tools before solid-organ transplantation.MethodsThe PRISMA search strategy and the MEDLINE database were used to revi

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